In this issue of Infectious Disease Clinics of North America, guest editors Drs. Alfred Luk and Luis Ostrosky-Zeichner bring their considerable expertise to the topic of Updates in Fungal Infections. Invasive fungal diseases remain an important cause of morbidity and mortality for certain patient populations, and many new developments in this area have occurred in the fields of medical mycology, epidemiological effects from climate change, fungal diagnostics, and antifungal therapeutics. In this issue, top experts cover the current state of the art in the understanding, diagnosis, and treatment of known and emerging fungal diseases.