The Rigel lab is a majors level manual that accompanies our Willey – Prescott’s Microbiology textbook. This laboratory manual provides a balanced introduction to laboratory techniques and principles that are important in each area of microbiology. Experiments follow the spirit of the ASM guidelines for laboratory content. Each experiment comes with a complete set of pedagogical aids—materials per group of students, learning objectives, pronunciation guide— so students understand the “how” and “why” of the labs in which they participate. This lab manual also comes with Connect and the Virtual Labs.